Browsing by Author "Odei, Judith"

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    Estimated dietary exposure to veterinary residues in chicken and eggs
    (International Journal of Food Contamination, 2015) Darko, Godfred; Mensah, John Kenneth; Dapaah, Sylvester Samuel; Odei, Judith; 0000-0001-7157-646X
    Background: Chicken tissues and eggs were analyzed for residues of eight veterinary drugs including albendazole, piperazine, tiamulin, chloramphenicol, levamisole, sulphathiazole, sulphamethoxazole and oxytetracycline oxytetracycline. Results: Mean residue concentrations of all drugs varied by tissue and ranged from 0.004 μg/kg for tiamulin in eggs to 8.6 μg/kg for chloramphenicol in liver. Total residues of all drugs in the liver generally exceeded that of the kidney, muscles and eggs by at least a two-fold difference. The general order of decreasing total drug residue levels is liver > kidney > muscle > eggs. The exposure due to albendazole and sulphamethoxazole in liver were 2- and 7-folds higher than their recommended average daily intake. Exposure due to piperazine, sulphamethoxazole, levamisole and tiamulin were, however, lower than their respective recommended limits. Conclusion: Dietary exposure assessments of all drugs based on quantitated residue levels are within the Joint FAO/ WHO Expert Committee on Food Additives safe regulatory exposure limits. This study informs the public about veterinary drug residues in poultry and helps address policy and regulatory changes in the use of veterinary drugs in poultry.
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    Veterinary Drug Residues in Chicken Eggs from Some Selected Poultry Farms in the Kumasi Metropolis, Kwabre East and Offinso Districts of the Ashanti Region
    (2015-02-23) Odei, Judith
    Multiresidue analyses of veterinary drugs were determined in commercial eggs from the Offinso, Kumasi Metropolis and the Kwabre East District in the Ashanti Region. A total of 200 table egg samples were collected for albendazole, chloramphenicol, levamisole, oxytetracycline, piperazine, sulphamethoxazole, sulphathiazole and tiamulin residuesfrom 5 poultry farms. Whole eggs were homogenized in acetonitrile, extracts evaporated and residues dissolved in mobile phase. The fats were removed using hexane. Extracts were analyzed by solid phase reverse phase high performance liquid chromatography with photodiode array detector. Results showed that Albendazole was the most frequently detected in all the 200 samples taken from the five farms in the three districts which occurred at an average concentration of 116.1± 2.30 µg/kg. Chloramphenicol was also detected at an average concentration of 26.6 ± 0.39µg/kg. Levamisole was recorded at an average concentration of 14.7 ± 0.26 µg/kg. Oxytetracycline residues registered an average concentration of 19.8 ± 0.47µg/kg.Piperazine was detected at an average concentration of 40.00 ± 0.80 µg/kg. The two sulphonamides,sulphamethoxazole and sulphathiazole had detectable concentrations of 17.05 ± 0.34µg/kg and32.50 ± 0.42 µg/kg respectively. The least detectable residue in all the five farms was tiamulin which had a detectable concentration of 0.95± 0.04 µg/kg. Detectable levels of all the drug residues were below their maximum residual limit given by the Joint FAO/WHO Expert Committee on Food Additives (JECFA).However the residues may accumulate to higher levels in human beings making them dangerous to human health.