Browsing by Author "Frempong, Bernard"

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    Clinical profile and predictors of viral suppression in HIV-infected older adults at a University Hospital in Kumasi, Ghana
    (AIDS Care, 2022) Ayisi-Boateng Nana Kwame; Opoku, Douglas Aninng; Nkrumah, Isaac; Frempong, Bernard; Owusu, Michael; Oduro, Eric; Ampah, Brenda Abena; Konadu, Emmanuel; Norman, Betty; 0000-0002-0961-4434; 0000-0003-2321-387X; 0000-0001-5066-150X
    Availability of effective antiretroviral therapy (ART) has improved patient survival and older adults (≥50 years old) constitute 10% of the world’s HIV population. However, data on this population are lacking, especially in sub-Saharan Africa. To identify the profile of older adults with HIV infection receiving ART and factors associated with viral suppression. A retrospective cross-sectional study involving HIV patients ≥50 years, registered at a University Hospital in Kumasi, Ghana from January 2010 to July 2020. All study participants had been on ARTs for ≥12 months. Data were analysed using STATA® and multivariate logistic regression was done to determine the association between variables. We recruited 132 study participants with a mean age of 58.1 years (±6.8). Non-communicable diseases (NCD) comprised the commonest comorbidity (67.4%;n = 89) and hypertension was the most prevalent (47.2%). The mean duration of ART was 63.2 months (±32.0) and approximately 84.1% (n = 111) achieved viral suppression (≤50 copies/ml). After adjustment, factors independently associated with viral suppression were widow(ed) (aOR = 0.23; 95% CI = 0.07–0.72) and good ART adherence (aOR = 3.51; 95% CI = 1.03–11.99). Hypertension is prevalent among this cohort of HIV patients. Approximately 84% of elderly patients on ARTs achieve viral suppression, influenced by widowhood and good drug adherence.