Browsing by Author "Adusi-Poku, Yaw"

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    Evaluation of the quality, safety and effectiveness of mist tonica in the management of anaemia, a case study
    (2005-11-10) Adusi-Poku, Yaw
    Anaemia is a widespread public health problem. In Ghana, anaemia is the fourth leading reason for hospital admissions and the second factor contributing to death. In managing anaemia, there have been various claims of the efficacy of some herbal formulae in raising haemoglobin concentration. The main objectives of this study sought to validate these claims by investigating the quality, clinical salty and effectiveness of an herbal medicine product in a hospital as a case study. Samples of the herbal medicine product were evaluated physico-chemically for their quality. The clinical study was carried out at the Seventh Day Adventist Hospital, Kwadaso, Kumasi. Patients were clinically selected and confirmed in the laboratory for anaemia. After signing informed consent forms, the patients were given doses of Mist Tonica, which was assessed for effectiveness and clinical safety. The main findings of the study are that, Mist Tonica produced by the Centre for Scientific Research into Plant Medicine, Mampong - Akwapim is safe to be used, as kidney and liver function tests were within normal range at the end of the study as well as fasting blood sugar, total white cell and platelets counts. Also, Mist Tonica is clinically effective. Statistical One —Sample T Test between Mist Tonica and allopathic haematinics (1 g/week rise of haemoglobin) revealed that at 95 % confident interval of the difference, the lower boundary was 0.6556 and the upper boundary was 1.2083. Also, an Independent- Sample T Test performed between Mist Tonica and a control population revealed that, t=8.13855 (calculated value) was greater than the textbook value of 3.232. Quality evaluation revealed significant variations in the mineral content of the batches of Mist Tonica, specifically iron, copper and aluminium. In conclusion, Mist Tonica is safe, effective and of appreciable quality.
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    Pregnant Women and Alcohol Use in the Bosomtwe District of the Ashanti Region
    (2011-08-29) Adusi-Poku, Yaw
    There are anecdotal claims that problem of alcohol ingestion exists among women in the reproductive years in the Bosomtwe district of the Ashanti Region but there is lack of data to support this. The principal objective of this study therefore was to validate these claims by the assessment of alcohol consumption among pregnant women attending antenatal clinics in the Bosomtwe District of the Ashanti Region. The study, a descriptive cross-sectional, was conducted in ten health facilities providing reproductive health care in the district in the months of July to October, 2010 with a sample size of 397 pregnant women. The main findings of the study were that 20.4% of pregnant women drank alcohol even though about three-quarters (78.0%) thought that alcohol had harmful effects in pregnancy. Fifty-seven percent (57.0%) of these (78.0%) did not actually know the possible harm that alcohol could cause on pregnancy. The most preferred drink was Akpeteshie, a locally manufactured distilled alcoholic beverage (36.4%), followed by Ginsing/Kasapreko/Pusher (27.3%). Study participants drank an average of ‘half-tot’ and ‘one-tot’ per a drinking session respectively. Logistic Regression analysis to identify the effects of some socio-demographic variables on alcohol consumption revealed that, Marital status and Religious affiliation were predictive of alcohol consumption, p< 0.10. It is recommended that the DHMT strengthens health education on alcohol at ANC and through the radio as well as the DHMT collaborating with the Ghana Health Service to embark on education of school pupils and students on the harmful effects of alcohol in pregnancy.