Qualitative and quantitative evaluation of cryptolepis-based herbal formulations in Ghana
| dc.contributor.author | Mensah, Adelaide | |
| dc.date.accessioned | 2016-02-02T13:05:44Z | |
| dc.date.accessioned | 2023-04-21T07:10:29Z | |
| dc.date.available | 2016-02-02T13:05:44Z | |
| dc.date.available | 2023-04-21T07:10:29Z | |
| dc.date.issued | 2015-11-02 | |
| dc.description | A Thesis submitted in partial fulfilment of the requirements for the award of Master of Philosophy Degree in Pharmaceutics, | en_US |
| dc.description.abstract | Cryptolepine is the first and main alkaloid isolated from the West African shrub Cryptolepis Sanguinolenta. Cryptolepine has been extensively studied and scientifically proven to exhibit antimuscarinic, antithrombotic, anti-inflammatory, anti-microbial, hypoglycaemic and antimalarial activities. It is also reported to be cytotoxic, being a DNA intercalator and a topoisomerase II inhibitor. In Ghana, Cryptolepis-based preparations which are mainly aqueous extracts of whole roots of Cryptolepis sanguinolenta are used as antimalarials. Currently, there are a number of branded Cryptolepis Sanguinolenta herbal formulations on the Ghanaian market. The proliferation of these brands calls for pharmacovigilance to ensure that spurious/falsely-labelled/falsified/counterfeit (SFFC) brands are identified to ensure the safety and quality of these formulations and hence improve malaria treatment outcomes. | en_US |
| dc.description.sponsorship | KNUST | en_US |
| dc.identifier.uri | https://ir.knust.edu.gh/handle/123456789/7947 | |
| dc.language.iso | en | en_US |
| dc.title | Qualitative and quantitative evaluation of cryptolepis-based herbal formulations in Ghana | en_US |
| dc.type | Thesis | en_US |
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