Clinical profile and predictors of viral suppression in HIV-infected older adults at a University Hospital in Kumasi, Ghana

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dc.contributor.authorAyisi-Boateng Nana Kwame
dc.contributor.authorOpoku, Douglas Aninng
dc.contributor.authorNkrumah, Isaac
dc.contributor.authorFrempong, Bernard
dc.contributor.authorOwusu, Michael
dc.contributor.authorOduro, Eric
dc.contributor.authorAmpah, Brenda Abena
dc.contributor.authorKonadu, Emmanuel
dc.contributor.authorNorman, Betty
dc.contributor.orcid0000-0002-0961-4434
dc.contributor.orcid0000-0003-2321-387X
dc.contributor.orcid0000-0001-5066-150X
dc.date.accessioned2024-02-21T10:51:24Z
dc.date.available2024-02-21T10:51:24Z
dc.date.issued2022
dc.descriptionThis is an article published by Nana Kwame Ayisi-Boateng, Douglas Aninng Opoku, Isaac Nkrumah, Bernard Frempong, Michael Owusu, Eric Oduro, Brenda Abena Ampah, Emmanuel Konadu & Betty Norman (2022): Clinical profile and predictors of viral suppression in HIV-infected older adults at a University Hospital in Kumasi, Ghana, AIDS Care, DOI: 10.1080/09540121.2022.2119468 To link to this article: https://doi.org/10.1080/09540121.2022.2119468
dc.description.abstractAvailability of effective antiretroviral therapy (ART) has improved patient survival and older adults (≥50 years old) constitute 10% of the world’s HIV population. However, data on this population are lacking, especially in sub-Saharan Africa. To identify the profile of older adults with HIV infection receiving ART and factors associated with viral suppression. A retrospective cross-sectional study involving HIV patients ≥50 years, registered at a University Hospital in Kumasi, Ghana from January 2010 to July 2020. All study participants had been on ARTs for ≥12 months. Data were analysed using STATA® and multivariate logistic regression was done to determine the association between variables. We recruited 132 study participants with a mean age of 58.1 years (±6.8). Non-communicable diseases (NCD) comprised the commonest comorbidity (67.4%;n = 89) and hypertension was the most prevalent (47.2%). The mean duration of ART was 63.2 months (±32.0) and approximately 84.1% (n = 111) achieved viral suppression (≤50 copies/ml). After adjustment, factors independently associated with viral suppression were widow(ed) (aOR = 0.23; 95% CI = 0.07–0.72) and good ART adherence (aOR = 3.51; 95% CI = 1.03–11.99). Hypertension is prevalent among this cohort of HIV patients. Approximately 84% of elderly patients on ARTs achieve viral suppression, influenced by widowhood and good drug adherence.
dc.description.sponsorshipKNUST
dc.identifier.citationNana Kwame Ayisi-Boateng, Douglas Aninng Opoku, Isaac Nkrumah, Bernard Frempong, Michael Owusu, Eric Oduro, Brenda Abena Ampah, Emmanuel Konadu & Betty Norman (2022): Clinical profile and predictors of viral suppression in HIV-infected older adults at a University Hospital in Kumasi, Ghana, AIDS Care, DOI: 10.1080/09540121.2022.2119468 ;To link to this article: https://doi.org/10.1080/09540121.2022.2119468
dc.identifier.urihttps://doi.org/10.1080/09540121.2022.2119468
dc.identifier.urihttps://ir.knust.edu.gh/handle/123456789/15511
dc.language.isoen
dc.publisherAIDS Care
dc.titleClinical profile and predictors of viral suppression in HIV-infected older adults at a University Hospital in Kumasi, Ghana
dc.typeArticle
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