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Title: In vitro anti-plasmodial activity of three herbal remedies for malaria in Ghana: Adenia cissampeloides (Planch.) Harms., Termina liaivorensis A. Chev, and Elaeis guineensis Jacq
Authors: Annan, Kofi
Sarpong, K.
Asare, C.
Dickson, R.
Amponsah, KI
Gyan, B.
Ofori, M.
Gbederna, SY.
Keywords: Adenia cissampeloides
Elaeis guineensis
Herbal remedies
Terminalia ivorensis
Issue Date: 11-Oct-2012
Publisher: Pharmacognosy Research
Citation: Pharmacognosy Research ,October-December 2012 , Vol 4 ,Issue 4
Abstract: Background: Herbal remedies of Adenia cissampe/oides, Terminalia ivorensis, and Elaeis guineensis among others have been used in Ghana for the treatment of various ailments including malaria. However, most of these remedies have not been scientifically investigated. Objective: This study, therefore, seeks to investigate the anti-plasmodial activity of these plants. Materials and Methods: The ethanolic extracts of A. cissampeloides stem, T. ivorensis stem bark, and E. guineensis leaves were tested for in vitro anti-plasmodial activitv against chloroquine-resistant strains of Plasmodium falciparum. Thin blood films were used to assess the level of parasitemia and growth inhibition of the extracts. Results: The IC50 of A. cissampeloides, T. ivorensis, and E. guineensis were 8.521, 6.949, and 1.195 Ilg/ml, respectively, compared to artesunate with IC50 of 0.031 Ilg/ml. Conclusion: The result of this study appears to confirm the folkloric anti-malarial use these plants.
Description: This is an article published by Pharmacognosy Research,October-December 2012,Vol 4 ,Issue 4
URI: http://hdl.handle.net/123456789/5137
Appears in Collections:College of Health Sciences

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