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Journal of Science and Technology 2000- >
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http://hdl.handle.net/123456789/5081
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| Title: | RP-LC Determination of Ascorbic Acid, Paracetamol and Caffeine in Multicomponent Anti-Cold Preparation |
| Authors: | Okine, N.N.A.
Asiedu, K.S.
Acheampong, J. |
| Keywords: | Ascorbic acid
Paracetamol
caffeine
benzoic acid
RP-LC |
| Issue Date: | 2003 |
| Publisher: | KNUST |
| Citation: | Journal of Science and Technology, Vol. 23 No.1, pp 54-61 |
| Abstract: | An RP-LC method for the simultaneous determination of ascorbic acid, paracetamol and caffeine in a tablet matrix is described. The mobile phase was a mixture of methanol-NaH2PO4 (17:83 pH 4.25 ±0.05) and stationary phase Aquapore RP-300. Total chromatographic time was approximately 8 minutes and the method found to be cost effective. The method was used to analyze some brands of multi-component anti cold preparations on the local market. Results were validated using the standard UV spectrophotometric methods for the assay of the individual components of these drugs. |
| Description: | Article published in the Journal of Science and Technology, Vol. 23 No.1, pp 54-61 |
| URI: | http://hdl.handle.net/123456789/5081 |
| ISSN: | 08550395 |
| Appears in Collections: | Journal of Science and Technology 2000-
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