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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/5081

Title: RP-LC Determination of Ascorbic Acid, Paracetamol and Caffeine in Multicomponent Anti-Cold Preparation
Authors: Okine, N.N.A.
Asiedu, K.S.
Acheampong, J.
Keywords: Ascorbic acid
benzoic acid
Issue Date: 2003
Publisher: KNUST
Citation: Journal of Science and Technology, Vol. 23 No.1, pp 54-61
Abstract: An RP-LC method for the simultaneous determination of ascorbic acid, paracetamol and caffeine in a tablet matrix is described. The mobile phase was a mixture of methanol-NaH2PO4 (17:83 pH 4.25 ±0.05) and stationary phase Aquapore RP-300. Total chromatographic time was approximately 8 minutes and the method found to be cost effective. The method was used to analyze some brands of multi-component anti cold preparations on the local market. Results were validated using the standard UV spectrophotometric methods for the assay of the individual components of these drugs.
Description: Article published in the Journal of Science and Technology, Vol. 23 No.1, pp 54-61
URI: http://hdl.handle.net/123456789/5081
ISSN: 08550395
Appears in Collections:Journal of Science and Technology 2000-

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