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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/13535

Title: Co-existence of malaria and urinary tract infection among children under five: A cross-sectional study of the Assin-South Municipality, Ghana
Authors: Ephraim, Richard K. D.
Nyame, M. A.
Sakyi, Samuel Asamoah
Antoh, E. O.
Simpong, D. L.
Keywords: Malaria
UTI
Antibiotic sensitivity pattern
Parasitaemia
Bacteriuria
Fever
Issue Date: 2013
Publisher: Journal of Medical and Biomedical Sciences
Citation: Journal of Medical and Biomedical Sciences (2013) 2(4): 35-41
Abstract: Across tropical Africa, febrile children are treated for malaria either with or without confirmation thus resulting in failure to diagnose and treat other co-morbidities like urinary tract infections (UTI) and upper respiratory tract infection (URTI) that may coexist with malaria. This cross-sectional study examined coexisting malaria with UTI and further assessed the antimicrobial sus-ceptibility pattern of the isolated organisms among children aged <5 years presenting with fever. Between December 2012 and May 2013, 284 children were recruited from the Saint Francis Xavier Hospital, in the Central Region of Ghana through purposive sampling. Thick and thin blood films were used for the diagnosis of malaria and urine samples were collected in sterile, wide-mouthed, leak proof containers for culture and sensitivity. Organisms isolated were identified and tested for their antimicrobial sensitivity patterns using the Kirby-Bauer disc diffusion method. Prevalence of malaria with coexisting UTI was 15.8% with majority (58.0%) of the participants being female. Age was significantly (p=0.025) associated with malaria and UTI co-infection with the highest preva-lence of co-infection (35.6%) recorded amongst the 13-24 months age group; gender was not asso-ciated with co-infection (p>0.05). Malaria parasitaemia (1+ to 3+) was significantly (p=0.001) asso-ciated with bacteriuria. Staphylococcus aureus (30.3%), Escherichia coli (20.4%) and Proteus spe-cies (5.3%) were isolated and these isolates were highly susceptible to Gentamicin (GEN), Ciprof-loxacin (CIP) and Nitrofurantoin (NIT) but were resistant to ampicillin (AMP). Staphylococcus aureus was the predominant cause of the UTI and the isolates were highly resistant to ampicillin but susceptible to gentamicin, ciprofloxacin and nitrofurantoin.
Description: An article published in Journal of Medical and Biomedical Sciences (2013) 2(4): 35-41
URI: http://hdl.handle.net/123456789/13535
Appears in Collections:College of Health Sciences

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