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|Title: ||Topic: Acute Kidney Injury in Children: 3-Year Data Review from Ghana|
|Authors: ||Antwi, Sampson|
Appia, Anna Serwaa
|Issue Date: ||2015|
|Publisher: ||International Journal of Pediatric Research|
|Abstract: ||Background/Aims: Acute kidney injury (AKI) is a relatively
common condition encountered in everyday paediatric practice. It
remains a significant contributor to preventable deaths especially
in resource constraint regions of the world largely due to lack of
This 3-year data analysis (2010-2012) was undertaken to determine
the aetiology and treatment/mortality outcomes of children with AKI
presenting to a Teaching Hospital in Ghana. AKI was defined in this
analysis by the RIFLE and KDIGO criteria.
Results: Two hundred and six (206) cases of AKI were recorded
over the period out of a total of 664 renal cases.
Haemoglobinuria, obstructive uropathy and tumour infiltration of the
kidneys were the leading causes of AKI (37.8%). 9.2% of cases
were diarrhoeal-related with glomerulonephritides occurring in
12.1% of cases.
Seventy-one (34.5%) of the 206 AKI cases required dialysis which
could only be provided for 25 (35.2%), 16 (64%) of whom survived.
Forty three (20.9%) children died, while 144 (69.9%) survived.
Thirty-one (72%) of the patients who died needed dialysis.
Conclusion: In comparison to previous studies across the world,
there is huge burden of AKI among hospitalized children in Kumasi,
Haemoglobinuria and tumour-related conditions accounted for
most cases of AKI more than diarrhoea-associated conditions and
postinfectious glomerulonephritis as were previously reported or
Most AKI deaths were related to lack of dialysis service. In view of
the less technical requirements compared with other modalities of
renal replacement therapy, peritoneal dialysis should be promoted
across Africa to curtail needless deaths from AKI.|
|Description: ||This article is published in International Journal of
|Appears in Collections:||College of Agric and Natural Resources|
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