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Title: | Blood Pressure and Haematological Indices in Twelve Communities in Ashanti, Ghana |
Authors: | Plange-Rhule, Jacob Kerry, Sally M. Eastwood, John B. Micah, Frank B. Antwi, Sampson Cappuccio, Francesco P. |
Issue Date: | 2018 |
Publisher: | Hindawi |
Citation: | Hindawi |
Abstract: | Cardiovascular disease has become an important cause of
premature death and disability in Sub-Saharan Africa [1, 2].
Hypertension is known to be the major contributor [3] and
is itself a consequence of increasing urbanisation and an
increasingly western lifestyle, exemplified by increasing obesity,
higher salt intake, and a sedentary lifestyle.
Another contributory factor to hypertension may be
blood viscosity. Plasma and whole blood viscosity have
been suggested as important determinants of arterial blood
pressure [4–9] both in normotensive individuals and in those
with untreated hypertension. Others, meanwhile, have suggested
that both blood pressure and viscosity are themselves
secondary to factors such as obesity, mental stress, smoking,
and physical inactivity [10]. Nonetheless, it is possible that
whole blood viscosity plays a part in the genesis of stroke and
coronary artery disease [11–15] and cardiac hypertrophy [16].
Of the factors contributing to whole blood viscosity, haematocrit,
red cell aggregability, red cell rigidity, and plasma
viscosity, haematocrit is thought to be the most important,
being responsible for at least 70% of the contribution [17].
However, others have not found a correlation between blood
pressure and blood viscosity in normotensives [18, 19].
Most of the evidence relating blood pressure to blood
viscosity is derived from studies from the developed world.
There is very little data on the relationship between blood
pressure and blood viscosity from Sub-Saharan Africa [20]. |
Description: | This article is published in Hindawi and also available at https://doi.org/10.1155/2018/5952021 |
URI: | http://hdl.handle.net/123456789/13520 |
ISSN: | 10.1155/2018/5952021 |
Appears in Collections: | College of Agric and Natural Resources
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