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|Title: ||Clinico-epidemiological profile and predictors of severe illness in young infants (0–59 days) in Ghana|
|Authors: ||YEBOAH-ANTWI, K.|
CARLIN, J. B.
OSEI AKOTO, Alex
WEBER, M. W.
HAMER, D. H.
|Issue Date: ||2017|
|Publisher: ||Annals of Tropical Paediatrics International Child Health|
|Abstract: ||Background: Young infant mortality has remained high and relatively unchanged compared with deaths of older
infants. Strategies to reduce infant mortality, however, are mostly targeted at the older child.
Objectives: To describe the clinical profile of sick young infants presenting to a hospital and to define important
signs and symptoms that will enable health workers to detect young infants with severe illness requiring hospital
Methods: Young infants aged 0–59 days presenting to a paediatric out-patient clinic were evaluated by a nurse using
a standardised list of signs and symptoms. A paediatrician independently evaluated these children and decided
whether they needed hospitalisation.
Results: A total of 685 young infants were enrolled, 22% of whom were ,7 days of age. The commonest reasons for
seeking care were jaundice in the 0–6-day group, skin problems in the 7–27-day group and cough in the 28–59-day
group. The primary clinical diagnoses for admissions were sepsis in the 0–6- and 7–27-day groups and pneumonia
in the 28–59-day group. Clinical signs and symptoms predicting severe illness requiring admission were general
(history of fever, difficult feeding, not feeding well and temperature .37.5uC) and respiratory (respiratory rate >60/
min, severe chest in-drawing).
Conclusion: General and respiratory signs are important predictors for severe illness in young infants. Training
peripheral health workers to recognise these signs and to refer to hospital for further assessment and management
might have a significant impact on young infant mortality.|
|Description: ||This article is published in Annals of Tropical Paediatrics International Child Health and also available at I: 10.1179/146532808X270653|
|Appears in Collections:||College of Agric and Natural Resources|
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