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Title: | Long-Term Outcomes of Stroke in a Ghanaian Outpatient Clinic |
Authors: | Sarfo, Fred Stephen Akassi, John Kyem, Gloria Adamu, Sheila Awuah, Dominic Sarfo-Kantanka, Osei Ovbiagele, Bruce |
Keywords: | Diabetes mellitus Ghana Long-term outcomes Stroke Survival |
Issue Date: | Apr-2018 |
Publisher: | Journal of Stroke and Cerebrovascular Diseases |
Citation: | Journal of Stroke and Cerebrovascular Diseases, Vol. 27, No. 4 (April), 2018: pp 1090–1099 |
Abstract: | Background: Compared with high-income countries, sub-Saharan African (SSA) countries
experience a comparatively higher early mortality from stroke. However, data
on long-term mortality from stroke in SSA are lacking. Objective: Our aim is to
assess long-term outcomes of stroke in an SSA setting. Methods: We conducted a
retrospective analysis of longitudinal data involving 607 consecutive stroke survivor
encountered at an outpatient clinic in Kumasi, Ghana, between January 2012
and June 2014. Data were closed for analysis in June 2016. Data on demography,
presence of vascular risk factors, stroke type, and functional status were evaluated.
We followed up subjects who were no longer attending clinic by phone to
assess their vital status. Primary outcome was death after initiation of clinic care,
and its predictors were determined using a Cox proportional hazards regression
model. Results: Mean ± standard deviation (SD) age of cohort was 59.9 ± 13.9 years
and 50.3% were female. Of the 607 stroke survivors, 377 (62.1%) were still alive,
59 (9.7%) were confirmed to have died, whereas 171 (28.2%) were lost to followup
at the clinic. Mean ± SD observation time for the cohort was 32 ± 30 months.
Upon adjustment for confounders, the independent predictors of mortality were
age (adjusted hazard ratio [aHR] of 1.41 [95% confidence interval 1.15-1.73] for a
10-year increase in age) and diabetes mellitus (aHR of 2.24 [1.32-3.80]). Conclusions:
Diabetes mellitus, a modifiable risk factor for stroke, is associated with an
increased risk of mortality among West African stroke survivors over the long
term. |
Description: | An article published in Journal of Stroke and Cerebrovascular Diseases, Vol. 27, No. 4 (April), 2018: pp 1090–1099; https://doi.org/10.1016/j.jstrokecerebrovasdis.2017.11.017 |
URI: | http://hdl.handle.net/123456789/13356 |
Appears in Collections: | College of Health Sciences
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