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|Title: ||Comparison of the clinical estimation of cup-to-disk ratio by direct ophthalmoscopy and optical coherence tomography|
|Authors: ||Ofeibea Amedo, Angela|
Koomson, Nana Yaa
Acquah, Emmanuel Kobia
Pascal, Tchiakpe Michel
Akowuah, Prince Kwaku
Djeagbo, Philip Tetteh
optical coherence tomography
|Issue Date: ||9-Jan-2019|
|Publisher: ||Therapeutic Advances in Ophthalmology|
|Citation: ||Therapeutic Advances in Ophthalmology|
|Abstract: ||Objective: To compare the clinical estimation of cup-to-disk ratio determined by direct
ophthalmoscopy and optical coherence tomography in glaucoma diagnosis and monitoring.
Methods: A retrospective, cross-sectional study involving a review of 71 optical coherence
tomography scans dating from June 2011 to January 2012 at a private imaging lab in Ghana.
At the respective referring facilities, only 31 out of the 71 corresponding patient records were
Results: Majority (54.84%) of the 31 patient records successfully reviewed were women.
The mean age was 44.54 ± 16.15 years. Cup-to-disk ratio was grouped into ⩽0.4, >0.4–0.6,
>0.6–0.8, and >0.8–1.0 based on direct ophthalmoscopy values. The overall mean cup-to-disk
ratio estimated by the optical coherence tomography and direct ophthalmoscopy were 0.72
± 0.21 and 0.60 ± 0.26, respectively. Overall, there was no statistically significant difference
in the mean cup-to-disk ratio estimation by direct ophthalmoscopy and optical coherence
tomography [right eye (p = 0.0629); left eye (p = 0.0766)]. There was a statistically significant
difference between direct ophthalmoscopy and optical coherence tomography cup-to-disk
ratio estimation for values ⩽0.4 [right eye (p = 0.0061); left eye (p = 0.0063)] and values
>0.4–0.6 [right eye (p = 0.0243); left eye (p = 0.0498)]. There was no statistically significant
difference between conventional direct ophthalmoscopy and optical coherence tomography
cup-to-disk ratio estimation for cup-to-disk ratio >0.6.
Conclusion: We recommend clinicians document which method they use in evaluating optic
nerve head parameters. This is to ensure that subsequent clinical decisions are not influenced
by an apparent change in these parameters, especially cup-to-disk ratio as different methods
might give different values.|
|Description: ||This article is published in Therapeutic Advances in Ophthalmology and is available in DOI: 10.1177/
|URI: ||10.1177/ 2515841418827268|
|Appears in Collections:||College of Science|
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