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|Title: ||Association of whole blood fatty acids and growth in Southern Ghanaian children 2–6 years of age|
|Authors: ||Adjepong, Mary|
Harris, William S.
Marquis, Grace S.
|Keywords: ||omega-3 index|
; long chain polyunsaturated fatty acids (LCPUFA)
|Issue Date: ||24-Jul-2018|
|Abstract: ||In Ghana, stunting rates in children below 5 years of age vary regionally. Dietary fatty
acids (FAs) are crucial for linear growth. The objective of this study was to determine the association
between blood FAs and growth parameters in southern Ghanaian children 2–6 years of age. A drop
of blood was collected on an antioxidant treated card and analyzed for FA composition. Weight and
height were measured and z-scores calculated. Relationships between FAs and growth were analyzed
by linear regressions and factor analysis. Of the 209 subjects, 22% were stunted and 10.6% were
essential FA deficient (triene/tetraene ratio > 0.02). Essential FA did not differ between stunted and
non-stunted children and was not associated with height-for-age z-score or weight-for-age z-score.
Similarly, no relationships between other blood fatty acids and growth parameters were observed
in this population. However, when blood fatty acid levels in these children were compared to
previously reported values from northern Ghana, the analysis showed that blood omega-3 FA levels
were significantly higher and omega-6 FA levels lower in the southern Ghanaian children (p < 0.001).
Fish and seafood consumption in this southern cohort was high and could account for the lower
stunting rates observed in these children compared to other regions.|
|Description: ||An article published by MDPI and also available at doi:10.3390/nu10080954|
|Appears in Collections:||College of Science|
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