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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/12866

Title: Phytochemical, antimicrobial, and antioxidant profiles of duranta erecta L. parts
Authors: Donkor, Shadrack
Larbie, Christopher
Komlaga, Gustav
Emikpe, Benjamin Obukowho
Issue Date: 24-Oct-2019
Publisher: Hindawi
Abstract: (e use of plant-based medicine is popular amongst individuals and communities in developing countries. Duranta erecta has been used in Africa and Asia to treat a wide range of diseases. (is study evaluated the phytochemical profile and antioxidant and antimicrobial activities of D. erecta to ascertain its health benefits in traditional medicine. Phytochemical constituents and antimicrobial effect of the hydroethanolic extract of D. erecta leaves (DRL), unripe fruits (DRU), and ripe fruits (DRR) were investigated by standard methods. Elemental analyses were carried out by atomic absorption spectroscopy (AAS) on the raw sample and extract. FTIR and UV-VIS spectroscopy were used to identify functional groups. Extracts were screened for their possible antioxidant activities by three tests. (e total phenolic and total tannin contents were evaluated by using the Folin– Ciocalteu method. Total flavonoid content was determined by the aluminium chloride colorimetric assay method. (e antioxidant activities were evaluated using the DPPH scavenging activity. (e results of phytochemical screening showed the presence of triterpenoids, sterols, alkaloids, flavonoids, saponins, glycosides, and tannins. FTIR analysis revealed the presence of alcohols, phenols, alkanes, aldehydes, ketones, aromatics, aliphatic amines, aromatic amines, amides, carboxylic acids, esters, nitro compounds, alkynes, primary and secondary amines, and alkyl halides. Iron, zinc, and copper were also detected. Total phenolic and tannin contents ranged from 2.20 ± 0.15 to 14.54 ± 0.29 mg gallic acid equivalent (GAE)/100 g and 3.55 ± 0.07 to 13.82 ± 0.04 mg GAE/100 g, respectively. Total flavonoid content varied from 41.76 ± 0.96 to 343.49 ± 3.45 μg quercetin equivalent (QE)/100 g. (e highest DPPH scavenging activity was recorded in the methanolic fraction of the leaves. (e antimicrobial assay of the extract or fractions recorded no activity against the test organisms. (e outcome of this study affirmed that D. erecta contains phytochemicals and bioactive compounds that could be of health benefit.
Description: An article published by Hindawi and also available at https://doi.org/10.1155/2019/8731595
URI: http://hdl.handle.net/123456789/12866
Appears in Collections:College of Science

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