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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/12854

Title: Phytochemical, antimicrobial, and antioxidant Profiles of duranta erectaL. parts
Authors: Donkor, Shadrack
Larbie, Christopher
Komlaga, Gustav
Emikpe, Benjamin Obukowho
Issue Date: 24-Oct-2019
Publisher: Hindawi
Abstract: (e use of plant-based medicine is popular amongst individuals and communities in developing countries.Duranta erectahasbeen used in Africa and Asia to treat a wide range of diseases. (is study evaluated the phytochemical profile and antioxidant andantimicrobial activities ofD. erectato ascertain its health benefits in traditional medicine. Phytochemical constituents andantimicrobial effect of the hydroethanolic extract ofD. erectaleaves (DRL), unripe fruits (DRU), and ripe fruits (DRR) wereinvestigated by standard methods. Elemental analyses were carried out by atomic absorption spectroscopy (AAS) on the rawsample and extract. FTIR and UV-VIS spectroscopy were used to identify functional groups. Extracts were screened for theirpossible antioxidant activities by three tests. (e total phenolic and total tannin contents were evaluated by using the Folin–Ciocalteu method. Total flavonoid content was determined by the aluminium chloride colorimetric assay method. (e antioxidantactivities were evaluated using the DPPH scavenging activity. (e results of phytochemical screening showed the presence oftriterpenoids, sterols, alkaloids, flavonoids, saponins, glycosides, and tannins. FTIR analysis revealed the presence of alcohols,phenols, alkanes, aldehydes, ketones, aromatics, aliphatic amines, aromatic amines, amides, carboxylic acids, esters, nitrocompounds, alkynes, primary and secondary amines, and alkyl halides. Iron, zinc, and copper were also detected. Total phenolicand tannin contents ranged from 2.20±0.15 to 14.54±0.29 mg gallic acid equivalent (GAE)/100 g and 3.55±0.07 to13.82±0.04 mg GAE/100 g, respectively. Total flavonoid content varied from 41.76±0.96 to 343.49±3.45μg quercetin equivalent(QE)/100 g. (e highest DPPH scavenging activity was recorded in the methanolic fraction of the leaves. (e antimicrobial assayof the extract or fractions recorded no activity against the test organisms. (e outcome of this study affirmed thatD. erectacontains phytochemicals and bioactive compounds that could be of health benefit.
Description: An article published by Hindawi and also available at https://doi.org/10.1155/2019/8731595
URI: http://hdl.handle.net/123456789/12854
Appears in Collections:College of Science

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