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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/12852

Title: Prevalence and determinants of diabetic foot ulcers and lower extremity amputations in three selected tertiary hospitals in Ghana
Authors: Atosona, Ambrose
Larbie, Christopher
Issue Date: 11-Feb-2019
Publisher: Hindawi
Abstract: Background. The occurrence and complications of diabetes are increasing worldwide. This study examined the prevalence anddeterminants of diabetic foot ulcers and lower extremity amputations in three selected tertiary hospitals in Ghana.Methods.Across-sectional multicenter study involving 100 subjects was carried out. Subjects were selected through simple randomsampling from three selected tertiary hospitals in Ghana. A structured questionnaire was used to document information onsociodemographic, medical history, lifestyle, and physical characteristics of subjects. Foot ulcers and lower extremityamputations were also investigated. Total cholesterol, triglycerides, low-density lipoproteins, high-density lipoproteins, serumurea, serum creatinine, and estimated glomerularfiltration rate of subjects were assessed. Data analysis was done using SPSSversion 22.Results. The study revealed that 31% and 69% were males and females, respectively, with a mean age of538±138years. Among the patients, 11% had diabetic foot ulcers whilst 3% had lower extremity amputations. In the multivariate binarylogistic regression analysis, previous history of foot ulcers (OR = 404, 95%CI = 55-299.9) and foot deformities (OR = 144, 95%CI = 13-161.2) were identified as independent predictors of diabetic foot ulcers. Foot deformity (p=0043) and serum urea(p=0002) were associated with diabetic lower extremity amputations in the univariate analysis.Conclusion. This study showedthat the prevalences of diabetic foot ulcers and lower extremity amputations are high among diabetes patients. Foot deformitiesand previous history of foot ulcers are determinants of diabetic foot ulcers. Foot deformity and serum urea are associated withdiabetic lower extremity amputations.
Description: An article published by Hindawi and also available at https://doi.org/10.1155/2019/7132861
URI: http://hdl.handle.net/123456789/12852
Appears in Collections:College of Science

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