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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/12726

Title: High prevalence of hepatitis B virus infection in the age range of 20-39 years old individuals in Lome
Authors: Kolou, Malewe
Katawa, Gnatoulma
Salou, Mounerou
Gozo-Akakpo, Komlan Selom
Kwarteng, Alexander
et. al
Keywords: Age range
HBs antigen
Hepatitis B virus
Prevalence
Togo
Issue Date: 7-Nov-2016
Publisher: Bentham Science Publishers
Abstract: Background:Hepatitis B is a liver infection caused by the hepatitis B virus (HBV). It affects all women and men irrespective of age. Althoughsub-Saharan Africa is an area of high prevalence of this disease, data on the prevalence of acute and chronic HBV infections in thisregion remain to be widely documented.Objective:This study aimed to investigate the prevalence of HBV in relation to age in Centre Hospitalier Universitaire Campus (CHU-C), oneof the two teaching hospitals of Lome, Togo.Method:The present study is a cross-sectional study about the prevalence of hepatitis B surface antigen (HBsAg) carriage from 2009 to 2011.All study participants were screened for HBsAg at the Immunology laboratory of CHU Campus of Lome.Results:One thousand two hundred individuals were screened for HBsAg from 2009-2011. The overall prevalence of HBV infection was19.08%. This prevalence was significantly higher in men (25.00%) than women (14.80%). The highest prevalence of HBV wasobserved in age range of 20-29 years and 30-39 years with respectively 26.33% and 21.67%. The lowest prevalence was 6.08%,found in people over 50 years. Concerning the clinical indication of the test, the prevalence during the clinical abnormalities relatedto liver (CARL) was the highest (26.21%), followed by the systematic screening (SS) with 20.25% while the pre-operativeassessment (POA) showed the lowest prevalence with 5.56%.Conclusion:The study shows the high prevalence of HBsAg carriage in young people. This could be used to enhance prevention and treatment ofHBV infection in Togo.
Description: An article published by Bentham Science Publishers and also available at DOI: 10.2174/1874357901710011001
URI: http://hdl.handle.net/123456789/12726
Appears in Collections:College of Science

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