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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/12720

Title: Influence of seasonal variation on reportedfilarial attacks among people living withlymphedema in Ghana
Authors: Kwarteng, Alexander
Arthur, Yarhands Dissou
Yamba, John Kanyiri
Sylverken, Augustina A.
Kini, Priscilla
et. al
Keywords: Lymphatic filariasis
Lymphedema
Adenolymphangitis
Ghana
Issue Date: 20-May-2019
Publisher: BMC Infectious Diseases
Citation: Kwartenget al. BMC Infectious Diseases (2019) 19:442 https://doi.org/10.1186/s12879-019-4084-2
Abstract: Background:Lymphatic Filariasis (LF) is a vector-borne neglected tropical disease caused by the filarial nematodeparasites that can lead to the disfiguring swelling of the limbs (lymphedema or elephantiasis for late stage) and/orgenitalia (hydrocele) in men. Growing evidence suggests that not only are filarial lymphedema patients confrontedwith huge societal stigma and discrimination, but also experience acute filarial attacks accompanied by swelling ofthe affected part(s), fever, wounds and peeling of the skin of affected limbs(s). However, the extent to whichseasonal variation influence filarial attacks among people with lymphedema was highly speculated withoutempirical evidence and was thus investigated.Methods:In light of this, a cross-sectional study where 142 (70.4% females and 29.6% males) lymphedema patientswere recruited from 8 established Wuchereria bancrofti endemic communities in the Ahanta West District, Ghanawas carried out to investigate the prevalence and seasonal variation (rainy/wet and dry seasons) of acute filarialattacks. Chi-square test was used to test for association between frequency of attacks and seasonality. The STROBEguidelines for reporting cross-sectional studies was adopted.Results:The average lymphedema leg stage was 2.37 and 2.33 for left and right legs, respectively, while mossylesions, sores and ulcers were observed among 33.1% of patients with late stage disease (elephantiasis). It wasfound that 97 (68.3%) of the study participants experience filarial attacks during the wet season and 36 (25.4%)reported the incidence of filarial attacks during both seasons (wet and dry) while 9 (6.3%) of the study participantsdid not experience any attack at all.Conclusions:Findings from the present study show compelling evidence that the frequency and the prevalence offilarial attacks is significantly increased during wet seasons compared to the dry season.
Description: An article published by BMC Infectious Diseases and also available at https://doi.org/10.1186/s12879-019-4084-2
URI: http://hdl.handle.net/123456789/12720
Appears in Collections:College of Science

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