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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/12511

Title: Distant Relatives of Severe Acute Respiratory Syndrome Coronavirus and Close Relatives of Human Coronavirus 229E in Bats, Ghana
Authors: Pfefferle, Susanne
Oppong, Samuel
Drexler, Jan Felix
Gloza-Rausch, Florian
Annan, Augustina
et. al
Issue Date: Sep-2009
Publisher: Centers for Disease Control and Prevention
Citation: Emerging Infectious Diseases. Vol. 15, No. 9, September 2009. DOI: 10.3201/eid1509.090224
Abstract: We tested 12 bat species in Ghana for coronavirus (CoV) RNA. The virus prevalence in insectivorous bats (n = 123) was 9.76%. CoV was not detected in 212 fecal samples from Eidolon helvum fruit bats. Leaf-nosed bats pertaining to Hipposideros ruber by morphology had group 1 and group 2 CoVs. Virus concentrations were <45,000 copies/100 mg of bat feces. The diversified group 1 CoV shared a common ancestor with the human common cold virus hCoV-229E but not with hCoV-NL63, disputing hypotheses of common human descent. The most recent common ancestor of hCoV-229E and GhanaBt-CoVGrp1 existed in ≈1686–1800 ad. The GhanaBt-CoVGrp2 shared an old ancestor (≈2,400 years) with the severe acute respiratory syndrome–like group of CoV.
Description: An article published by Centers for Disease Control and Prevention and also available at DOI: 10.3201/eid1509.090224
URI: http://hdl.handle.net/123456789/12511
Appears in Collections:College of Science

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