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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/12083

Title: In vitro anti-plasmodial activity of three herbal remedies for malaria in Ghana: Adenia cissampeloides (Planch.) Harms., Termina liaivorensis A. Chev, and Elaeis guineensis Jacq
Authors: Annan, Kofi
Sarpong, K.
Asare, C.
Dickson, R.
Amponsah, KI.
Gyan, B.
Ofor, M.
Gbedema, SY.
Keywords: Adenia cissampeloides
Elaeis guineensis
herbal remedies
Issue Date: Oct-2010
Publisher: Pharmacognosy Research
Citation: Pharmacognosy Research, Vol 4 | Issue 4
Abstract: Background: Herbal remedies of Adenia cissampeloides, Terminalia ivorensis, and Elaeis guineensis among others have been used in Ghana for the treatment of various ailments including malaria. However, most of these remedies have not been scientifically investigated. Objective: This study, therefore, seeks to investigate the anti-plasmodial activity of these plants. Materials and Methods: The ethanolic extracts of A. cissampeloides stem, T. ivorensis stem bark, and E. guineensis leaves were tested for in vitro anti-plasmodial activity against chloroquine-resistant strains of Plasmodium falciparum. Thin blood films were used to assess the level of parasitemia and growth inhibition of the extracts. Results: The IC50 of A. cissampeloides, T. ivorensis, and E. guineensis were 8.521, 6.949, and 1.195 µg/ml, respectively, compared to artesunate with IC50 of 0.031 µg/ml. Conclusion: The result of this study appears to confirm the folkloric anti-malarial use these plants
Description: This article is published in Pharmacognosy Research and also available at DOI: 10.4103/0974-8490.102270
URI: 10.4103/0974-8490.102270
Appears in Collections:College of Health Sciences

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