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|Title: ||Clinical Evaluation of the Safety and Effectiveness of Adutwumwaa Malamix: A Polyherbal Product for the Treatment of Uncomplicated Malaria in Ghana|
|Authors: ||Tetteh, Andrews W.|
Mensah, Merlin L.
Boadu, Kwame O.
Thomford, Kwesi P.
Agyemang, Michael O.
Dickson, Rita A.
Mensah, Abraham Y.
Amposah, Isaac K.
Owusu-Ansah, Emmanuel D. J
|Keywords: ||Adutwumwaa malamix|
safety and effectiveness
|Issue Date: ||Jul-2017|
|Publisher: ||Journal of Applied Pharmaceutical Science|
|Citation: ||Journal of Applied Pharmaceutical Science, Vol. 7 (07), pp. 040-045,|
|Abstract: ||Antimalarial medications remain one of the major interventional tools for the global malaria control efforts. One
of the most popular Ghanaian herbal antimalarial agent is the product sold under the trade name ‘Adutwumwaa
malamix’. This product is registered with the Food and Drugs Authority (FDA) of Ghana as treatment of
uncomplicated malaria. In this study, the safety and effectiveness of the product ‘Adutwumwaa malamix’ for the
treatment of uncomplicated malaria was clinically evaluated based on disease-oriented and patient-oriented
evidence. A total of 42 subjects were recruited for the study. Complete cure was achieved for 35 (83.33%) of
participants by day 7 of the study. Partial efficacy was also achieved for 7 (16.66%) of subjects. Patient reported
symptoms such fever, chills and abdominal pains were also significantly improved by day 7 and absent by day
28. The safety parameters assessed did not show any clinically significant change among the study population
during treatment. The outcome of the study indicates that the Ghanaian herbal antimalarial agent ‘Adutwumwaa
malamix’ may be an effective herbal treatment for the management of uncomplicated malaria.|
|Description: ||This article is published in Journal of Applied Pharmaceutical Science and also available at DOI: 10.7324/JAPS.2017.70706|
|Appears in Collections:||College of Health Sciences|
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