DSpace
 

KNUSTSpace >
Research Articles >
College of Health Sciences >

Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/12069

Title: EVALUATION OF WOUND HEALING ACTIONS OF HOSLUNDIA OPPOSITA VAHL, ANTHOCLEISTA NOBILIS G. DON. AND BALANITES AEGYPTIACA L
Authors: Annan, K.
Dickson, Rita A.
Keywords: Wound healing
antioxidant
Hoslundia opposita
Hoslundia opposita
Anthocleista nobilis
Balanites aegyptiaca
Issue Date: Aug-2008
Publisher: Journal of Science and Technology
Citation: Journal of Science and Technology, Vol. 28, No. 2
Abstract: Hoslundia opposita, Anthocleista nobilis and Balanites aegyptiaca are widely used ethnomedicinally in Ghana in the treatment of skin diseases. In this context, antimicrobial potential of the three plant species against a wide range of microorganisms was studied. To validate the ethnotherapeutic claims of these plants in skin diseases, in vivo wound healing activity was studied, besides antioxidant activity to understand the mechanism of wound healing. Methanol extract of Hoslundia opposita showed significant antibacterial activity against all bacteria tested including some resistant strains of Staphyloccocus aureus, with MIC ranging between 64-256 µg/ml. The results show that all three extracts have potent wound healing activity as evident from the wound contraction, increased tensile strength and hydroxyproline content. The results also indicated that the three plant species possess potent antioxidant activity by inhibiting lipid peroxidation, bleaching DPPH radical and protecting against oxidant injury to fibroblast cells.
Description: This article is published in Journal of Science and Technology and also available at DOI: 10.4314/just.v28i2.33091
URI: 10.4314/just.v28i2.33091
http://hdl.handle.net/123456789/12069
Appears in Collections:College of Health Sciences

Files in This Item:

File Description SizeFormat
Evaluation of Wound Healing Actions of Hoslundia Opposita Vahl, Anthocleista Nobilis G. Don. and Balanites Aegyptiaca L..pdf79.11 kBAdobe PDFView/Open

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

 

Valid XHTML 1.0! DSpace Software Copyright © 2002-2010  Duraspace - Feedback