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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/11965

Title: Dietary Patterns Are Associated with Predicted 10-Year Risk of Cardiovascular Disease Among Ghanaian Populations: the RODAM Study
Authors: Boateng, Daniel
Galbete, Cecilia
Nicolaou, Mary
Meeks, Karlijn
Beune, Erik
Smeeth, Liam
Osei-Kwasi, Hibbah Araba
Bahendeka, Silver
Agyei-Baffour, Peter
Mockenhaupt, P
Spranger, Joachim
Grobbee, Diederick E
Schulze, Matthias B
Stronks, Karien
Agyemang, Charles
Danquah, Ina
Klipstein-Grobusch, Kerstin
Keywords: dietary patterns
cardiovascular disease risk
pooled cohort equation
sub-Saharan Africa
RODAM study
Issue Date: Apr-2019
Publisher: ASN, Journal of Nutrition
Citation: Journal of Nutrition 00:1-15
Abstract: Background: Sub-Saharan African populations are disproportionately affected by CVD. Although diet is an important lifestyle factor associated with CVD, evidence on the relation between dietary patterns (DPs) and CVD risk among subSaharan African populations is limited. Objective: We assessed the associations of DPs with estimated 10-y atherosclerotic cardiovascular disease (ASCVD) risk in Ghanaian adults in Ghana and Europe. Methods: Three DPs (‘mixed’; ‘rice, pasta, meat, and fsh’; and ‘roots, tubers, and plantain’) were derived by principal component analysis (PCA) based on intake frequencies obtained by a self-administered Food Propensity Questionnaire in the multi-center, cross-sectional RODAM (Research on Obesity and Diabetes among African Migrants) study. The 10-y ASCVD risk was estimated using the Pooled Cohort Equations for 2,976 subjects, aged 40–70 y; a risk score ≥7.5% was defned as ‘elevated’ ASCVD risk. The associations of DPs with 10-y ASCVD risk were determined using Poisson regression with robust variance. Results: Stronger adherence to a ‘mixed’ DP was associated with a lower predicted 10-y ASCVD in urban and rural Ghana and higher 10-y ASCVD in Europe. The observed associations were attenuated after adjustment for possible confounders with the exception of urban Ghana (prevalence ratio [PR] for Quintile 5 compared with 1: 0.70; 95% CI: 0.53, 0.93, P-trend = 0.013). The ‘rice, pasta, meat, and fsh’ DP was inversely associated with 10-y ASCVD across all study sites, with the adjusted effect being signifcant only in urban Ghana. A ‘roots, tubers, and plantain’ DP was directly associated with increased 10-y ASCVD risk. Conclusions: Adherence to ‘mixed’ and ‘rice, pasta, meat, and fsh’ DPs appear to reduce predicted 10-y ASCVD risk in adults in urban Ghana. Further investigations are needed to understand the underlying contextual-level mechanisms that influence dietary habits and to support context-specifc dietary recommendations for CVD prevention among subSaharan African populations. J Nutr 2019;00:1–15.
Description: This article is published in The Journal of Nutrition and available at DOI: 10.1093/jn/nxz002
URI: DOI: 10.1093/jn/nxz002
Appears in Collections:College of Health Sciences

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