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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/11866

Title: Mycobacterium ulcerans disease
Authors: Stienstra, Ymkje
Johnson, R. Christian
Phillips, Richard O.
Adjei, Ohene
Fleischer, Bernhard
et. all
Issue Date: Oct-2005
Publisher: Bulletin of the World Health Organization
Citation: Bulletin of the World Health Organization 2005;83:785-791.
Abstract: Mycobacterium ulcerans disease (Buruli ulcer) is an important health problem in several west African countries. It is prevalent in scattered foci around the world, predominantly in riverine areas with a humid, hot climate. We review the epidemiology, bacteriology, transmission, immunology, pathology, diagnosis and treatment of infections. M. ulcerans is an ubiquitous micro-organism and is harboured by fish, snails, and water insects. The mode of transmission is unknown. Lesions are most common on exposed parts of the body, particularly on the limbs. Spontaneous healing may occur. Many patients in endemic areas present late with advanced, severe lesions. BCG vaccination yields a limited, relatively short-lived, immune protection. Recommended treatment consists of surgical debridement, followed by skin grafting if necessary. Many patients have functional limitations after healing. Better understanding of disease transmission and pathogenesis is needed for improved control and prevention of Buruli ulcer.
Description: An article published by Bulletin of the World Health Organization
URI: http://hdl.handle.net/123456789/11866
Appears in Collections:College of Health Sciences

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