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|Title: ||Low seroprevalence of cryptococcal antigenaemia in patients with advanced HIV infection enrolling in an antiretroviral programme in Ghana|
|Authors: ||Mamoojee, Yaasir|
Gorton, Rebecca L.
Phillips, Richard O.
|Keywords: ||Cryptococcus, HIV, Africa, epidemiology, cryptococcal antigen|
|Issue Date: ||Jan-2011|
|Publisher: ||Tropical Medicine and International Health|
|Citation: ||Tropical Medicine and International Health volume 16 no 1 pp 53–56|
|Abstract: ||objectives To determine the prevalence of cryptococcal antigenaemia in a clinic population with
advanced HIV infection, with a view to giving antifungal therapy to those testing positive.
methods Serum samples from adults with CD4 count <100 cells ⁄mm3 presenting to a large HIV clinic
in Kumasi, Ghana, were tested retrospectively for cryptococcal antigenaemia using a latex agglutination
assay, and clinical and demographic data extracted from case notes.
results Of 92 samples tested, two were positive thus giving a prevalence of 2% (95% CI, 0–5.2%).
conclusions The prevalence of cryptococcal antigenaemia in patients with advanced HIV infection
enrolling in an antiretroviral programme appears to be low in Kumasi, suggesting that the value of
routine testing of outpatients diagnosed with advanced HIV infection may be limited in this population.|
|Description: ||An article published by Tropical Medicine and International Health and is available at doi:10.1111/j.1365-3156.2010.02683.x|
|Appears in Collections:||College of Health Sciences|
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