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|Title: ||Hepatitis C in Sub-Saharan Africa: Urgent Need for Attention|
|Authors: ||Layden, Jennifer E.|
Phillips, Richard O.
Salako, Babatunde L.
|Keywords: ||Africa; epidemiology; hepatitis C; transmission.|
|Issue Date: ||Jul-2014|
|Publisher: ||Oxford University Press|
|Citation: ||Oxford University Press|
|Abstract: ||The hepatitis C virus (HCV), which was not recognized as an infectious agent until the 1980s, is responsible for
a worldwide epidemic. The World Health Organization estimates global prevalence at 2.8%, with 185 million
persons infected. In contrast to hepatitis B, where successful vaccine campaigns have reduced the disease burden,
much less progress has been made toward the control of HCV. Phylogenetic studies suggest that HCV originated
in Africa and has been endemic in some regions for at least 500–600 years. However, little is known about
the epidemiology, transmission, and clinical course of HCV in Africa. With the advent of highly effective anti-
HCV agents, there exists great potential to at least curb the global epidemic. For regions such as sub-Saharan
Africa, however, this will require a thorough understanding of the regional population-level epidemiology, risk
factors, and transmission mechanisms. Only then can effective treatment and prevention strategies be
|Description: ||An article published by Oxford University Press and is available at DOI: 10.1093/ofid/ofu065|
|Appears in Collections:||College of Health Sciences|
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