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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/11815

Title: Antimicrobial Agents: Antibacterial agents, anti-biofilm agents, antibacterial natural compounds, and antibacterial chemicals
Authors: Boakye, Yaw Duah
Osafo, Newman
Danquah, Cynthia Amaning
Adu, Francis
Agyare, Christian
Keywords: antimicrobials
biofilm inhibitors
natural products
antibacterials
Issue Date: 2016
Publisher: Intech Open
Citation: Intech Open DOI: http://dx.doi.org/10.5772/intechopen.82560
Abstract: The surge in antimicrobial resistance coupled with the decline in the antimicrobial drug pipeline calls for the discovery and development of new agents to tackle antibiotic resistance and prevent a return to a post-antibiotic era. Several factors account for resistance of microbes; some are natural and others are acquired. Natural selection, presence of efflux pumps, impermeable cell wall, biofilm formation and quorum sensing are some of the factors. Though it is difficult to outwit the pathogens, the discovery and development of compounds with pleiotropic modes or mechanisms of action different from the conventional drugs currently being used can help us tackle antimicrobial resistance. Natural products have been known to be a rich source of bioactive compounds with diverse structures and functional group chirality. Various reports indicate medicinal plants with antibacterial, anti-biofilm, efflux pump inhibition, wound healing effects or properties and others used for upper respiratory and urinary tract infections. There is an urgent need to research into natural products particularly plants for antimicrobial agents including antibacterial agents, anti-biofilm agents, antibacterial natural compounds and antibacterial chemicals. This chapter throws more light on such antimicrobials.
Description: An article published by Intech Open and available at DOI: http://dx.doi.org/10.5772/intechopen.82560
URI: http://hdl.handle.net/123456789/11815
Appears in Collections:College of Health Sciences

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