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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/11122

Title: Prevalence of Dyslipidemia and Atherogenic Risk among Type 2 Diabetic Outpatients in Ghana
Authors: Asamoah-Boakye, O.
Apprey, Charles
Keywords: Dyslipidemia
Atherogenic index
Type 2 diabetes Mellitus
Issue Date: May-2017
Publisher: International Journal of Public Health and Clinical Sciences
Citation: International Journal of Public Health and Clinical Sciences; Vol. 4:No. 3
Abstract: Background: Dyslipidemia is a major risk factor for cardiovascular diseases, which in turn contribute 68% of mortality among type 2 diabetics. The study aimed to determine dyslipidemia and atherogenic index, among Type 2 diabetic outpatients in Ghana. Methods: A cross sectional study was conducted on 152 participants. Anthropometric and biochemical indices (including glycated hemoglobin and lipid profile) were determined. Result: Thirty-seven (24.3%) participants were males and 115 (75.7%) were females. Prevalence of hyperglycemia was 74.3%. The prevalence of single dyslipidemia, combined dyslipidemia and mixed dyslipidemia were 63.8%, 15.8%, and 1.3% respectively. Also, 35.3% of the participants had high coronary risk and 5.3% had high atherosclerotic risk. Coronary risk was strongly associated with Total Cholesterol (TC), (r=0.690, p< 0.0001) and Low density lipoprotein Cholesterol (LDL-C), (r=0.783, p< 0.0001), while atherosclerotic risk correlated with Triglycerides (TG), (r=0.817, p< 0.0001) and Very low density lipoprotein Cholesterol (VLDL-C), (r=0.817, p< 0.0001). Regression analyses revealed that a point increase in TC was associated with 2.6-folds increased odds of coronary disease risk (OR= 2.6, 95% CI=1.9-3.7, p< 0.0001), TG was associated with 2-folds higher coronary risk (OR= 2.5, 95% CI= 1.3-4.8, p=0.004), and LDL-C was associated with 5- folds higher coronary disease risk (OR= 4.9, 95% CI=2.9-8.1, p< 0.0001) among participants. Conclusion: Uncontrolled blood glucose and atherogenic dyslipidemia was common among these diabetics, were significantly associated with high coronary and atherosclerotic risk. Management of diabetes in Ghana needs a critical look at to increase effectiveness and reduce the burden of the disease.
Description: An article published by International Journal of Public Health and Clinical Sciences; Vol. 4:No. 3, 2017
URI: http://hdl.handle.net/123456789/11122
Appears in Collections:College of Science

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