DSpace
 

KNUSTSpace >
Research Articles >
College of Health Sciences >

Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/10720

Title: Antibiotic Susceptibility Patterns of Salmonella Typhi among Patients in Three Hospitals in Kumasi, Ghana
Authors: Saana, S.B. Bayaa Martin
Adu, F.
Gbedema, S. Y.
Duredoh, F. G.
Keywords: Salmonella typhi
Antiobiotics
Susceptibility
Multiple-drug resistance
Issue Date: 2014
Publisher: IJPSR
Citation: IJPSR, 2014; Vol. 5(3): 855-860.
Abstract: Salmonella typhi, causative agent of typhoid fever, a predominantly human communicable disease, is endemic in Africa and Asia. S. typhi is of clinical importance partly due to its mode of infection and partly due to the fact that human activities such as poor hygienic conditions are essential in the transmission and perpetuation of the pathogen. More so antibiotic resistant strains of S. typhi have emerged, increasing cost of treatment, morbidity and mortality. Meanwhile, S. typhi isolation and sensitivity testing to antibiotics are rarely practiced in the hospitals in and around Kumasi. This study sought to determine the extent of antibiotic susceptibility of S. typhi isolated from patients in Kumasi south, North Suntreso and Tafo hospitals in the Ashanti region of Ghana. The isolates were identified using morphological and biochemical means. The isolates were then tested for their sensitivity to some reference antibiotics using the Kirby-Bauer disc diffusion method. One hundred and twenty-eight (128) S. typhi were isolated from 900 clinical samples. A total of 52.3% of the S. typhi isolates exhibited resistance to ampicillin whereas 32.8, 25.0, 17.2 and 14.9% of the isolates were resistant to co-trimoxazole, chloramphenicol, ciprofloxacin and ceftriaxone respectively. About 19.5% of the S. typhi isolates were multidrug resistant. The S. typhi isolates were most sensitive to ciprofloxacin and ceftriaxone whilst majority of the S. typhi tested were resistant to ampicillin. Ampicillin is therefore no longer suitable for the treatment of S. typhi infections in these hospitals.
Description: An article published by IJPSR, 2014; Vol. 5(3): 855-860.
URI: http://hdl.handle.net/123456789/10720
Appears in Collections:College of Health Sciences

Files in This Item:

File Description SizeFormat
ANTIBIOTIC SUSCEPTIBILITY PATTERNS OF SALMONELLA TYPHI AMONG PATIENTS IN THREE HOSPITALS IN KUMASI, GHANA.pdf362.62 kBAdobe PDFView/Open

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

 

Valid XHTML 1.0! DSpace Software Copyright © 2002-2010  Duraspace - Feedback