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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/10716

Title: Self-reported adverse reactions associated with topical ophthalmic medication use: a cross-sectional survey
Authors: Kyei, Samuel
Koffuor, George Asumeng
Ameyaw, Elvis Ofori
Ramkissoon, Paul
Adu-Agyeman, Daniel
Issue Date: 2014
Publisher: Drugs and Therapy Studies
Citation: Drugs and Therapy Studies 2014; volume 4:5278
Abstract: The aim of this study was to investigate selfreported adverse reactions associated with the use of topical ophthalmic medications. A crosssectional survey, involving 500 ophthalmic patients recruited from three eye care facilities in the Central Region of Ghana was conducted. A structured questionnaire was administered to participants to collect data on demographics, name of drug, dosage form, and dosing frequency of ophthalmic medications used, as well as adverse reactions experienced. The pHs of frequently prescribed ophthalmic medications to the patients were measured. The prevalence of reported adverse drug reaction [predominantly burning sensation (55%), blurry vision (22%) and itching (13%)] was 44.8%. More Females reported adverse drug reactions than males (χ2=26.24, P<0.001). The aged reported more adverse reaction than others (P<0.01). Patients using cream ophthalmic medications reported more adverse drug reactions than those using other dosage forms (χ2=8.80, P=0.024). The pHs of the commonly prescribed ophthalmic medications measured ranged between 4.44- 7.37 (desired: 6.6-7.8). There is a high prevalence of reported symptoms of adverse drug reactions among this clinical population attributable to the acid/base status of the drug agent
Description: An article published by Drugs and Therapy Studies 2014; volume 4:5278
URI: http://hdl.handle.net/123456789/10716
Appears in Collections:College of Health Sciences

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